Masters Thesis-Nanocarrier Development for Immune Cell Targeting (f/m/x)
Master's Thesis – Nanocarrier Development for Immune Cell Targeting (f/m/x)
102909
Part time
20 hrs./week
Neuherberg near Munich
Partial Home Office possible
At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.
At the Institute for Intelligent Biotechnologies (iBIO) our major goal is to accelerate biomedical research by developing and combining enabling technologies. Our major research fields are AI-based organ mapping, Tissue engineering and Precision medicine in cancer treatments. Sophisticated technologies such as 3D tissue imaging, molecular profiling are combined with AI tools to decode the complexity of tissues and shed light into cancer biology.
Our interdisciplinary team — comprising biologists, engineers, computer scientists, and medical researchers — develops next-generation computational models to interpret complex biomedical data across multiple scales. Our innovations in tissue clearing, 3D microscopy, and AI-driven pathology have been featured in leading journals (Nature Methods, Nature Neuroscience, Cell, Nature Biotechnology) and major media (The New York Times, Wall Street Journal, Süddeutsche Zeitung).
We are seeking a motivated Master's student (f/m/x) with a background in biochemistry, bioengineering, or a related field. The thesis project focuses on the development of lipid nanoparticle (LNP) libraries designed to achieve targeted delivery to immune cell populations.
Your tasks
- Design and evaluation of targeting ligands (e.g., peptides)
- LNP formulation and ligand conjugation
- Physicochemical characterization of nanocarriers
- Library screening using barcoding approaches
- Performance analysis in tissue-cleared mice using light-sheet microscopy
- Quantitative assessment of immune organ and cell-type targeting
Your profile
- Enrolled Master's student in Bioengineering, Biochemistry, Biomedical Sciences, or related discipline
- Solid laboratory experience is required
- Interest in nanotechnology and drug delivery
- Structured, independent working style with ability to work collaboratively in an interdisciplinary team
Desirable qualifications
- Experience with peptide design or in silico tools is a plus
- Experience in primer design, PCR, sequencing is a plus
This position has a fixed term, depending on the requirements of your study program.
Managing Director Mike Frieser:
„We believe that diversity is the key to groundbreaking research and innovative solutions. Our flexible working models and remote options create a supportive environment for balancing work and family life. For us, contributing to a healthier society in such an inspiring workplace is truly meaningful.“
Interested in applying?
If you have any questions, feel free to contact Stefanie Reitinger, stefanie.reitinger@helmholtz-munich.de, who will be happy to help.